Below is a selection of my recent research work.

Spline refinement with differentiable rendering
Frans Zdyb, Albert Alonso, J. B. Kirkegaard
Under Review · March 2025
This work introduces a training-free differentiable rendering approach to spline refinement, achieving both high reliability and sub-pixel accuracy. It serves as a drop-in replacement for the popular active contour model.
Adaptive Node Positioning in Biological Transport Networks
Albert Alonso, Lars Erik J. Skjegstad, J. B. Kirkegaard
Under Review · November 2024
This work generalizes the hydrodynamic graph model, allowing for additional optimization of node positioning. It results in organic networks that adapt to boundary irregularities and node misalignment while improving overall efficiency.

Local Clustering and Global Spreading of Receptors for Optimal Spatial Gradient Sensing
Albert Alonso, Robert G. Endres, J. B. Kirkegaard
Published · April 2025
Using a theoretical model, this study explores how receptors cluster in high-curvature membrane regions, optimizing spatial gradient sensing and aligning with real-cell observations.

Persistent pseudopod splitting is an effective chemotaxis strategy in shallow gradients
Albert Alonso, J. B. Kirkegaard, Robert G. Endres
Published · May 2025
A minimal model that provides a quantitative understanding of how cells use pseudopod splitting to achieve high-performance chemotaxis with minimal regulation.

Irreversibility in Non-reciprocal Chaotic Systems
Tuan Pham, Albert Alonso, Karel Proesmans
Published · February 2025
This study develops a stochastic-thermodynamic framework to analyze the relationship between irreversibility and dynamical behavior in high-dimensional chaotic systems.
Learning optimal integration of spatial and temporal information in noisy chemotaxis
Albert Alonso, J. B. Kirkegaard
Published · July 2024
This study finds that the transition between chemotaxis strategies is continuous and that a combined strategy outperforms constrained variants and explicit spatial-temporal integration models.

Fast detection of slender bodies in high-density microscopy data
Albert Alonso, J. B. Kirkegaard
Published · July 2023
An end-to-end deep learning approach for extracting precise shape trajectories of motile, overlapping slender bodies, applied to dense experiments of swimming nematodes.

Simulations of strongly coupled ions at a liquid-gas interface in time projection chambers
Albert Alonso
B.Sc. Thesis · 2019
This thesis explores the behavior of strongly coupled ions at liquid-gas interfaces, providing insights for time projection chambers in physics experiments.